Shedding of tissue factor (TF)-containing microparticles rather than alternatively spliced TF is the main source of TF activity released from human cancer cells
نویسندگان
چکیده
منابع مشابه
Ratio of transferrin (Tf) to Tf-receptor complex in circulation differs depending on Tf iron saturation.
Circulation Differs Depending on Tf Iron Saturation, Junji Kato, Masayoshi Kobune, Yutaka Kohgo, Koshi Fujikawa, Rishu Takimoto, Yoshihiro Torimoto, Yoshihisa Ito, Masami Bessho, Tomomitsu Hotta, Akihisa Hikawa, Takafumi Fujii, Kari Punnonen, and Yoshiro Niitsu ( The Fourth Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo 060-8543, Japan; 2 Third Departmen...
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Background: Tissue factor (TF) serves as the primary initiator of the extrinsic pathway of blood coagulation and mediates signaling via the protease activated receptor-2 (PAR2). TF is over-expressed in several tumor types and may facilitate tumor progression and angiogenesis. To test the hypothesis that inhibition of TF may have an anti-tumor effect, we induced pulmonary adenomas (PA) in human ...
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Previous studies from this group have shown that limit size lipid-based systems – defined as the smallest achievable aggregates compatible with the packing properties of their molecular constituents – can be efficiently produced using rapid microfluidic mixing technique. In this work, it is shown that similar procedures can be employed for the production of homogeneously sized unilamellar vesic...
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Purpose: We aim to evaluate the repeatability of a new fluorescence lifetime imaging (FLIM) technique which measures time-resolved autofluorescence to assess metabolism of the retina. Materials and methods: We performed FLIM with two spectral channels (channel 1: 490–560 nm and channel 2: 560–700 nm) on 10 healthy volunteers, with 10 replicates per volunteer. From the 30 fundus FLIM images, we ...
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With ever increasing use of imaging as a diagnostic tool in medicine, medical schools are being urged to further integrate imaging into their curricula. Ultrasound is one such way of doing so-enabling students to bridge the gap between form and function, medical school and clinical practice. As a non-invasive imaging technique, with low risk when compared to other methods of imaging, ultrasound...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2004
ISSN: 1538-7933,1538-7836
DOI: 10.1111/j.1538-7836.2004.00972.x